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Related Experiment Videos

Medication safety: a protocol for nursing action. NICHE Faculty.

M K Walker1, M D Foreman

  • 1College of Nursing, University of South Florida, Tampa, USA.

Geriatric Nursing (New York, N.Y.)
|May 8, 1999
PubMed
Summary

Older adults experience significant medication-related adverse events, with many prescriptions written for them. This review explores how aging affects drug metabolism and suggests strategies to mitigate risks for seniors.

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Prevalence of undiagnosed Type 2 diabetes and impaired fasting glucose in older British men and women.

Diabetic medicine : a journal of the British Diabetic Association·2005

Area of Science:

  • Gerontology
  • Clinical Pharmacology
  • Pharmacoepidemiology

Background:

  • Medication use is prevalent in older Americans, accounting for 25%-40% of U.S. prescriptions.
  • Adverse drug events, therapeutic misadventure, and toxicity are significant concerns for this population.
  • Hospital admissions for drug-related issues in elders can be as high as 33%.

Purpose of the Study:

  • To examine physiological changes associated with aging.
  • To understand the impact of aging on medication absorption, distribution, and metabolism.
  • To identify high-risk medications and propose strategies to manage adverse effects in older adults.

Main Methods:

  • Review of physiological changes in aging.
  • Analysis of pharmacokinetic alterations in elders.
  • Identification of high-risk drug classes and adverse event mitigation strategies.

Main Results:

  • Aging alters drug absorption, distribution, and metabolism.
  • Specific medications pose higher risks for older individuals.
  • Effective strategies exist to manage and prevent adverse drug events.

Conclusions:

  • Understanding age-related physiological changes is crucial for safe medication management in older adults.
  • Proactive identification and management of high-risk medications can reduce adverse events.
  • Implementing targeted strategies can improve therapeutic outcomes and patient safety for elders.

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