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Immune activation in non-treated suicidal major depression
S Mendlovic1, E Mozes, E Eilat
1Shalvata Mental Health Center, Hod-Hasharon, Israel. mendlov@netvision.net.il
Immunology Letters
|May 8, 1999
Abstract:
In the following study we have analyzed cytokine secretion of T-cells of suicidal and non-suicidal depressed patients and healthy controls. It was found that T-cells of suicidal depressed patients have Th1 characteristics, while T-cells of non-suicidal depressed patients have Th2 characteristics. Th1 environment is associated with most of autoimmune diseases. It is thus speculated that Th1 activation in suicidal depression may reflect a unique form of autoimmune suicide.