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Neurofibromatosis and pregnancy
British Journal of Obstetrics and Gynaecology
|November 1, 1978
Summary
Neurofibromatosis, a genetic disorder, does not appear to cause specific obstetric complications in pregnancy. Most pregnancies in affected women proceeded without adverse events, suggesting a generally safe obstetric course.
Area of Science:
- Obstetrics and Gynecology
- Medical Genetics
Background:
- Neurofibromatosis is a group of genetic disorders.
- Potential obstetric implications require investigation.
Purpose of the Study:
- To investigate the association between neurofibromatosis and obstetric complications.
- To assess pregnancy outcomes in women with neurofibromatosis.
Main Methods:
- Retrospective case series.
- Analysis of 27 pregnancies in 10 patients with neurofibromatosis.
Main Results:
- Two patients experienced pre-eclampsia in their first pregnancy only.
- No other adverse obstetric features were observed in the remaining pregnancies.
- The overall obstetric course was largely uncomplicated.
Conclusions:
- Neurofibromatosis is not specifically associated with significant obstetric complications.
- Further case reporting is needed to confirm these findings.