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The voiding pattern in infants with dilating reflux
U Sillén1, A L Hellström, G Holmdahl
1Departments of Paediatric Surgery and Urotherapy, Sahlgren's University Hospital Ostra, Göteborg, Sweden.
Insights
Infants with dilating vesico-ureteric reflux (VUR) exhibit distinct voiding patterns compared to healthy infants, indicating potential bladder dysfunction. These differences vary between boys and girls.
Area of Science:
- Pediatric Urology
- Nephrology
- Infant Health
Background:
- Vesico-ureteric reflux (VUR) is a common condition in infants.
- Understanding voiding patterns may reveal underlying bladder dysfunction in VUR.
- Previous studies established voiding patterns in healthy infants.
Purpose of the Study:
- To compare the voiding patterns of infants with dilating VUR to those of healthy infants.
- To investigate if voiding pattern differences support bladder dysfunction in VUR.
- To identify sex-specific voiding characteristics in infants with VUR.
Main Methods:
- A noninvasive 4-hourly voiding record was utilized.
- Forty-one infants with dilating VUR (grades 3-5) were studied.
- Results were compared with a cohort of healthy infants of similar age.
Main Results:
- Boys with VUR showed more frequent, smaller, and interrupted voids than healthy boys.
- Girls with VUR presented as infrequent voiders with higher volumes.
- Both boys and girls with VUR had significantly increased residual urine and bladder capacity.
Conclusions:
- The voiding pattern in infants with dilating VUR differs significantly from healthy infants.
- Observed voiding characteristics suggest bladder dysfunction in refluxing infants.
- Sex-specific voiding patterns in VUR align with invasive urodynamic findings.
Objective:
To determine whether the voiding pattern in infants with dilating vesico-ureteric reflux (VUR) differs from that in healthy infants, thus supporting the existence of bladder dysfunction in infants with VUR.
Patients And Methods:
Forty-one infants (33 boys and eight girls) with dilating VUR (grades 3-5) were studied using a noninvasive 4-hourly voiding record described previously in studies of the voiding pattern of healthy infants, and the results compared with those obtained from healthy infants of similar age.
Results:
The voiding pattern in the boys with VUR was characterized by small frequent voids and interrupted voids in more patients (36%) than in healthy boys (15%). Conversely, the girls with VUR were infrequent voiders of relatively high volumes. Residual urine was significantly increased in both boys and girls, as was bladder capacity, although not significantly.
Conclusions:
The free voiding pattern in infants with dilating reflux differs from that seen in healthy infants of comparable age. The characteristics for boys and girls differed but was in accordance with that seen in invasive urodynamic studies, suggesting refluxing infants to have a bladder dysfunction.
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