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Rowell's syndrome.

F J Child1, N Kapur, D Creamer

  • 1St. John's Institute. of Dermatology, St. Thomas' Hospital, London, UK. fionachild@hotmail.com

Clinical and Experimental Dermatology
|May 8, 1999
PubMed
Summary
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Rowell's syndrome, a rare lupus erythematosus variant, presents with erythema multiforme-like skin lesions and specific antibodies. This case highlights its distinct clinical and serological features in a patient with lupus.

Area of Science:

  • Dermatology
  • Rheumatology
  • Immunology

Background:

  • Rowell's syndrome is a rare condition characterized by lupus erythematosus, erythema multiforme-like lesions, and a specific serological profile.
  • It represents a distinct variant of cutaneous lupus erythematosus.

Observation:

  • A case study of a 29-year-old Afro-Caribbean woman presenting with an erythema multiforme-like rash on her hands.
  • The patient subsequently developed painful, swollen, erythematous lesions on her feet and scaly plaques on her forearm and thigh, indicative of subacute cutaneous lupus erythematosus.

Findings:

  • The patient exhibited a positive antinuclear factor, positive anti-Ro and anti-La antibodies, and a positive rheumatoid factor.
  • These serological findings, combined with the clinical presentation, are consistent with a diagnosis of Rowell's syndrome.

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Implications:

  • This case reinforces Rowell's syndrome as a rare but distinct entity within the spectrum of cutaneous lupus erythematosus.
  • Understanding these distinct features is crucial for accurate diagnosis and management of patients with complex lupus presentations.