Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Seborrhoeic dermatitis].

Y Sei1, A Nakabayashi

  • 1Department of Dermatology, Showa University Fujigaoka Hospital, Fujigaoka 1-30, Aoba-ku, Yokohama, 227-8501, Japan.

Nihon Ishinkin Gakkai Zasshi = Japanese Journal of Medical Mycology
|May 11, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In vivo bioluminescence imaging of transplanted bone marrow mesenchymal stromal cells using a magnetic delivery system in a rat fracture model.

The Journal of bone and joint surgery. British volume·2012
Same author

Radial nerve palsy with hourglass-like constrictions in a child.

The Journal of hand surgery, European volume·2012
Same author

Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms.

Molecular psychiatry·2007
Same author

Microreview of Pityriasis versicolor and Malassezia species.

Mycopathologia·2006
Same author

Molecular analysis of malassezia microflora from patients with pityriasis versicolor.

Mycopathologia·2006
Same author

[Relationship between Malassezia Yeast and Infantile Seborrhoeic Dermatitis].

Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·2001

Seborrhoeic dermatitis (SD) is linked to Malassezia yeast. Antifungal treatments effectively reduce SD lesions and have lower recurrence rates than corticosteroids, offering a promising alternative therapy.

Area of Science:

  • Dermatology
  • Mycology
  • Microbiology

Background:

  • The etiology of seborrhoeic dermatitis (SD) remains unclear, with previous research suggesting a link to Malassezia yeast.
  • The Malassezia genus has been recently revised, identifying seven distinct species.

Purpose of the Study:

  • To investigate the presence and species of Malassezia in healthy individuals and patients with seborrhoeic dermatitis.
  • To evaluate the efficacy of antifungal agents compared to corticosteroids in treating seborrhoeic dermatitis.

Main Methods:

  • Malassezia spores were detected and quantified on skin using direct counting (cellotape strips) and culture.
  • Malassezia strains were identified to the species level using Guillot's Tween test.
  • Treatment outcomes for antifungal agents and corticosteroids were compared, focusing on lesion reduction and recurrence rates.

Related Experiment Videos

Main Results:

  • Higher Malassezia spore counts were observed in male students compared to females.
  • No correlation was found between spore numbers and sebum levels.
  • Malassezia globosa and Malassezia furfur were identified as the primary species associated with seborrhoeic dermatitis.
  • Antifungal treatment led to lesion elimination, paralleling a reduction in Malassezia spore counts.
  • Antifungal therapy demonstrated significantly lower recurrence rates compared to corticosteroid treatment.

Conclusions:

  • Malassezia yeasts, particularly M. globosa and M. furfur, are strongly associated with seborrhoeic dermatitis.
  • Antifungal agents represent a valuable therapeutic option for seborrhoeic dermatitis, offering sustained remission and potentially serving as an alternative to corticosteroids.