[Embolization of hepatic artery in liver cirrhosis complicated by ascites: long-term results]

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P G Tarazov

    Khirurgiia
    |May 11, 1999
    PubMed

    Insights

    Embolisation of the hepatic artery (EHA) showed limited long-term effectiveness for treating cirrhosis with ascites. This interventional radiology procedure is not recommended over conservative treatments for liver cirrhosis complications.

    Area of Science:

    • Hepatology
    • Interventional Radiology
    • Gastroenterology

    Background:

    • Cirrhosis of the liver frequently leads to portal hypertension and ascites, significantly impacting patient prognosis.
    • Current treatment strategies for complicated cirrhosis aim to manage symptoms and improve survival rates.

    Purpose of the Study:

    • To evaluate the efficacy and outcomes of hepatic artery embolisation (EHA) compared to conservative drug treatment in patients with liver cirrhosis and ascites.
    • To assess the impact of EHA on ascites regression and patient survival across different Child-Pugh classifications.

    Main Methods:

    • Retrospective analysis of 199 patients diagnosed with liver cirrhosis and complicated ascites.
    • Comparison between 130 patients who underwent EHA and 69 patients receiving conventional drug therapy.
    • Survival rates and ascites regression were analyzed, with stratification by Child-Pugh class (A, B, C).

    Main Results:

    • EHA demonstrated a 3% mortality rate. Ascites initially regressed in 55% of EHA patients, but this effect persisted in only 27% at 12 months.
    • No significant survival differences were observed between EHA and chemotherapy for Child-Pugh classes A and C.
    • Conservative treatment showed a more favorable prognosis for patients in Child-Pugh class B.

    Conclusions:

    • Hepatic artery embolisation (EHA) provides only short-term ascites regression in liver cirrhosis patients.
    • EHA is not recommended as a primary treatment for liver cirrhosis complicated by portal hypertension and ascites.
    • Management strategies should consider patient stratification (Child-Pugh class) for optimal outcomes.

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