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4D Printed Bifurcated Stents with Kirigami-Inspired Structures
Published on: July 25, 2019
Simple and complex stent strategies for bifurcated coronary arterial stenosis involving the side branch origin
M Pan1, J Suárez de Lezo, A Medina
1Hospital Reina Sofía, University of Córdoba, Spain.
Insights
Treating coronary bifurcation stenosis with stents is challenging. A simpler technique, stent jail followed by balloon dilation, showed better long-term outcomes than complex bifurcation reconstruction.
Area of Science:
- Interventional Cardiology
- Cardiovascular Surgery
Background:
- Coronary bifurcation lesions present significant challenges for stent implantation.
- Maintaining side branch patency after stenting is crucial but complex.
Purpose of the Study:
- To compare the outcomes of two different stent implantation techniques for coronary bifurcation stenosis.
- To evaluate the efficacy and safety of simpler versus complex stenting strategies.
Main Methods:
- A study of 70 patients with coronary bifurcation stenosis treated between 1994 and 1998.
- Two techniques were compared: (A) single stent in the parent vessel with side branch balloon angioplasty, and (B) complex reconstruction with multiple stents.
- Follow-up was conducted at 18 months.
Main Results:
- Procedural success rates were similar between the two groups (89% vs 91%).
- Major adverse cardiac events at 18 months were significantly higher in the complex reconstruction group (44% vs 75% event-free probability, p <0.05).
Conclusions:
- Selected patients with coronary bifurcation stenosis can be treated effectively with stenting.
- Complex stent reconstruction techniques for bifurcations do not offer advantages over simpler methods like stent jail and balloon dilation.
Abstract:
Coronary lesions located in major bifurcations constitute a challenge for the use of stents. Although the occlusion of a side branch covered by a stent is infrequent, the maintenance of a patent, stenosis-free bifurcation may result in a complex procedure. Between September 1994 and April 1998, 70 patients were treated by stent implantation for coronary bifurcation stenosis. The side branch always had a diameter >2 mm. The pairs of treated arteries were: left anterior descending (LAD)/diagonal artery in 32 patients, circumflex/obtuse marginal in 26, right coronary/posterior descending artery in 5, and LAD/circumflex in 7. We applied 2 different techniques of stent implantation: (1) deployment of 1 stent in the parent vessel covering the takeoff of the side branch and subsequent angioplasty of the side branch across the metallic structure (group A, n = 47 patients), and (2) implantation of 1 stent at the ostium of the side branch and complete reconstruction of the entire bifurcation with additional implantation of 1 or 2 stents at the parent vessel (group B, n = 23 patients). There were no significant differences between groups at baseline variables. Procedural success was similar in both groups: 42 (89%) in group A versus 21 (91%) in group B. However, major cardiac events at 18 months follow-up were higher in group B (event-free probability 44% vs 75%, p <0.05). Selected patients with coronary stenosis at major bifurcations can be treated with an acceptable rate of primary and late success. Complex techniques providing radical stent reconstruction of the bifurcation seems to provide no advantages over the simpler stent jail followed by ostial side branch balloon dilation.
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