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Intrasellar paraganglioma presenting as nonfunctioning pituitary adenoma
D Sambaziotis1, G Kontogeorgos, K Kovacs
1Department of Pathology and Neurosurgery, G. Gennimatas Athens General Hospital, Greece.
Archives of Pathology & Laboratory Medicine
|May 11, 1999
Summary
Sellar region paragangliomas are rare tumors. This case highlights an intrasellar paraganglioma presenting as a sellar mass, diagnosed via histology and immunocytochemistry.
Area of Science:
- Neuro-oncology
- Endocrinology
- Pathology
Background:
- Paragangliomas are rare tumors that can occur in the sellar region.
- Sellar masses are typically presumed to be pituitary adenomas.
Observation:
- A 54-year-old man presented with progressive vision loss and bitemporal hemianopsia.
- Magnetic resonance imaging showed a large sellar mass, initially suspected to be a nonfunctioning pituitary adenoma.
Findings:
- Histologic, immunocytochemical, and electron microscopic analyses confirmed the sellar mass as a paraganglioma.
- The tumor exhibited characteristic morphologic and immunocytochemical features of paraganglioma.
Implications:
- This case expands the differential diagnosis for sellar region masses.
- Accurate diagnosis of intrasellar paraganglioma is crucial for appropriate management and patient outcomes.