Related Experiment Video
Updated: Oct 22, 2026

Liquid Chromatography Coupled to Refractive Index or Mass Spectrometric Detection for Metabolite Profiling in Lysate-based Cell-free Systems
Published on: September 23, 2021
Abstract:
The description of an I.V. admixture profile form is presented. Detailed information on the mechanisms of using this form, as well as the advantages of the profiling system, are delineated. Several examples are illustrated for thorough understanding of the system. The authors conclude that the system affords a simple, accurate, and flexible profiling system which can be utilized in hospital I.V. admixture programs of various sizes. The profiling system provides for a mechanism of clinical involvement as well as for quality assurance assessment.
Related Concept Videos
One-Compartment Model: IV Infusion
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
Two-Compartment Open Model: IV Infusion
The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...
One-Compartment Open Model for IV Bolus Administration: General Considerations
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant, half-life,...
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
Two-Compartment Open Model: IV Bolus Administration
The disparity between drug input and the sum of drug transfer rates between...
Ion-Exchange Chromatography
