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Developing an adverse drug reaction program in nursing homes.

J A Soon

    The Canadian Journal of Hospital Pharmacy
    |August 9, 1980
    PubMed
    Summary
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    Adverse drug reactions: why should they be reported?

    The Canadian journal of hospital pharmacy·1979

    Pharmacists identified that 27% of nursing home patients experienced moderate to severe adverse drug reactions, with most being preventable. Increased pharmacy involvement significantly reduced hospitalizations, highlighting the value of clinical pharmacy services in geriatric care.

    Area of Science:

    • Geriatric Pharmacy
    • Pharmacovigilance
    • Drug Safety

    Background:

    • Adverse drug reactions (ADRs) are a significant concern in geriatric populations, particularly in long-term care settings.
    • A formalized reporting system is crucial for detecting and managing unwanted drug effects in elderly patients.

    Purpose of the Study:

    • To determine the incidence of adverse drug reactions in geriatric nursing home patients.
    • To identify drug classes most frequently associated with ADRs.
    • To evaluate the impact of pharmacist-led interventions on ADRs and hospitalizations.

    Main Methods:

    • A prospective study involving 826 geriatric nursing home patients.
    • Utilized a formalized adverse drug reaction reporting program for detection.
    • Analyzed drug-related data and pharmacist recommendations.

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    Main Results:

    • Approximately 27% of patients experienced moderate to severe adverse drug effects.
    • Five drug groups accounted for 75% of detected reactions; most were predictable and preventable.
    • Females over 70 on multiple medications were more susceptible to ADRs.
    • Physicians implemented 76% of pharmacist recommendations, reducing drug-induced hospitalizations.

    Conclusions:

    • Adverse drug reactions are common and often preventable in geriatric nursing home residents.
    • Enhanced pharmacist involvement in patient care can significantly reduce ADRs and hospitalizations.
    • Findings are generalizable to other geriatric care settings, advocating for expanded clinical pharmacy services.