Is automated urinalysis in your laboratory's future?

Examination of the urine, possibly the earliest diagnostic test in medicine, has only recently benefited from automation; one previous twentieth-century advance was substitution of specific reagents for earlier nonspecific chemical tests that were subject to interferences. In the mid-1970s, semiautomated urinalysis instruments were developed to read and record chemical test reactions used in manual urinalysis. Further, in 1984 the first instrument coupling automated intelligent microscopy (AIM) with a dipstick reader became available, fully automating both the biochemical screening and microscopic examination of urine specimens. This assessment describes AIM, as embodied in the Yellow IRIS instrument, and also discusses alternative strategies that laboratorians are developing to improve the cost effectiveness of conventional urinalysis.