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Updated: Aug 14, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Abstract:
While expert systems hold great promise for decision support, currently available software packages, called decision-modelling programs, provide clinicians with analytical assistance for resolving difficult decisions. This paper describes the two general classes of computerized decision-modelling programs (decision tree analysis and multiple criteria models), and illustrates the descriptions with examples of commercially available packages. Decision tree analysis is useful when the selection of a present action (for example, a treatment) depends on some outcome in the future (i.e. the occurrence of side effects). Multiple criteria models help clinicians when the choice of action depends on satisfying many criteria simultaneously.
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