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Pharmacist-based i.v. theophylline therapy.

T Donahue, J Dotter, G Alexander

Hospital Pharmacy

|May 9, 1989

Summary

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A new protocol for intravenous theophylline dosing and monitoring was implemented. This approach ensured that 84% of patients remained within the target therapeutic range of 10-20 mcg/mL.

Area of Science:

Pharmacology
Clinical Pharmacy Practice
Patient Safety

Background:

Theophylline is a critical medication requiring careful dosing.
Inconsistent theophylline levels can lead to toxicity or sub-therapeutic effects.
A standardized protocol is needed for safe and effective IV theophylline administration.

Purpose of the Study:

To implement and evaluate a protocol for intravenous theophylline dosing and monitoring.
To ensure consistent therapeutic theophylline levels in patients.
To improve patient safety and treatment efficacy.

Main Methods:

Development and implementation of a pharmacist-driven protocol for IV theophylline.
Individualized dosing based on clinical criteria and patient history.

Related Experiment Videos

Ongoing monitoring and dosage adjustments.

Quality assurance audits to assess adherence to therapeutic range.

Main Results:

The implemented protocol successfully maintained therapeutic theophylline levels (10-20 mcg/mL) in 84% of patients.
Pharmacist involvement ensured individualized dosing and monitoring.
Quality assurance audits validated the protocol's effectiveness.

Conclusions:

A pharmacist-led protocol for IV theophylline dosing and monitoring is effective.
This protocol significantly improves the maintenance of therapeutic theophylline levels.
Implementation enhances patient safety and optimizes theophylline therapy.