[Frequency-optimal pacing in chronic pacemaker therapy]

Hemodynamic studies were performed in 15 pacemaker patients at rest and during exercise by thermodilution technique and impedance cardiography. Particularly in myocardial failure, individual optimal heart rates were observed, ranging from 90 to 120/min. Mean increase of cardiac output at optimal pacing rate was 1.31/min against stimulation at 70/min. Impedance cardiography showed high correlation to thermodilution technique.