[Manometric studies on the influence of selective proximal vagotomy on the lower esophageal sphincter]

Selective proximal vagotomy (SPV) decreases the LES pressure (resting pressure and pentagastrin-stimulated pressure), significantly 6 months postoperatively without achieving LES insufficiency by clinical means. Immediately after stimulation LES pressure is identical, compared to preoperative measurements. Concentration of serum gastrin is not a major determinant of LES tone in humans.