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Synthesis of Mannich bases of antineoplaston A10 and their antitumor activity

B G Choi¹, H K Seo, B H Chung

¹College of Pharmacy, Chonnam National University, Kwangju, Korea.

Archives of Pharmacal Research

|December 1, 1994

Abstract:

Some Mannich bases of Antineoplaston A10 which is antitumor agent under clinical investigation were synthesized and tested for cytotoxicity. The tested compounds (2a, 2b, 2d) showed good activity comparable to that of carboplatin.

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