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Effect of xanthine oxidase inhibitor on myocardial ischemia
Recent Advances in Studies on Cardiac Structure and Metabolism
|May 26, 1976
Abstract:
The xanthine oxidase inhibitor, 4-hydroxypyrazolo(3,4-d) pyrimidine (HPP), Allopurinol, caused augmentation of myocardial uptake of [3H] hypoxanthine, which was eventually completely incorporated into ATP. The decrease of [32P] orthophosphate incorporation into ATP induced by isoproterenol was restored by HPP administration.