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Inflammatory pseudotumors of the lung
R J Cerfolio1, M S Allen, A G Nascimento
1Section of General Thoracic Surgery and Division of Anatomic Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA.
The Annals of Thoracic Surgery
|May 13, 1999
Summary
Inflammatory pseudotumors of the lung are rare but can be locally invasive. Complete surgical resection is safe and leads to excellent survival rates for this unusual lung pathology.
Area of Science:
- Thoracic Surgery
- Surgical Pathology
- Pulmonary Medicine
Background:
- Inflammatory pseudotumors of the lung are uncommon and pose surgical challenges.
- This study reviews the Mayo Clinic's experience with this rare lung pathology.
Purpose of the Study:
- To review the clinical experience with inflammatory pseudotumors of the lung.
- To evaluate the outcomes of surgical resection for lung inflammatory pseudotumors.
Main Methods:
- A retrospective review of 23 patients who underwent resection for inflammatory pseudotumor of the lung between 1946 and 1993.
- Analysis of patient demographics, symptoms, surgical procedures, tumor characteristics, and follow-up data.
- Pathologic specimens were re-reviewed to confirm the diagnosis.
Main Results:
- Complete resection was achieved in 78% of patients, with no operative deaths.
- The overall 5-year survival rate was 91%, with most deaths unrelated to the pseudotumor.
- Recurrence occurred in 3 of 5 patients with incomplete resection, but subsequent complete excision was successful.
Conclusions:
- Inflammatory pseudotumors of the lung are rare, can be large and locally invasive, and frequently require significant pulmonary resection.
- Complete surgical resection is safe and associated with excellent long-term survival.
- Re-resection should be considered for recurrent pseudotumors.