A comparative analysis of Class II treatments: a retrospective/prospective alternative
1Department of Orthodontics and Pediatric Dentistry, University of Michigan, Ann Arbor 48109-1078, USA. lejjr@umich.edu
Abstract:
Because of a perceived need to examine problems more pressing than 'now versus later' or 'headgear versus functionals', a retrospective/prospective alternative to the randomized clinical trial has been developed. In this approach, discriminant analysis is used to identify samples of ex-patients who, prior to treatment, were equally susceptible to various contemporary treatment alternatives: extraction, non-extraction; orthodontics, surgery; fixed versus functional. This method of 'confounder summarization' has made it possible for us to conduct a wide variety of long-term comparisons and, in the process, to assess treatment efficiency, stability, esthetics, functional impact, and interaction with the pattern of facial growth. These studies are described in broad outline and serve as examples of the type of data that can be generated in a timely fashion by carefully planned, quasi-experimental investigations.
More Related Videos
06:55Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
10:46A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Related Concept Videos
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Comparing the Survival Analysis of Two or More Groups
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Clinical Trials
There are four phases in a clinical trial. A phase one...
Blind Procedures
