Related Experiment Video
Updated: Aug 10, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Graft-like plantar lesion secondary to possible dorsal-to-ventral cutaneous transposition
L Dragan1, A L Lorincz, M M Medenica
1Section of Dermatology, University of Chicago, Illinois 60637, USA.
Abstract:
We describe a 3-year-old male patient with an unusual congenital lesion on the plantar surface of the left foot that had been asymptomatic until shortly before presentation. Histologic examination of the plaque revealed a thinner keratin layer, increased pigmentation, and a pilosebaceous unit with a visible vellus hair. We tentatively hypothesize from this single case that a disruption in the normal sequence of events of morphogenesis, and particularly in dorsal-to-ventral orientation, may have occurred in this patient.

