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Ichthyosiform sarcoidosis.

J C Cather1, P R Cohen

  • 1Department of Dermatology, University of Texas-Houston Medical School, USA.

Journal of the American Academy of Dermatology
|May 13, 1999
PubMed
Summary
This summary is machine-generated.

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Ichthyosiform sarcoidosis, a rare skin condition resembling acquired ichthyosis, was observed in a patient with chronic obstructive pulmonary disease. Skin biopsy confirmed sarcoidosis, highlighting the need for evaluation of acquired ichthyosis.

Area of Science:

  • Dermatology
  • Internal Medicine

Background:

  • Ichthyosiform sarcoidosis is a rare cutaneous manifestation of sarcoidosis.
  • It presents clinically and microscopically as acquired ichthyosis.

Observation:

  • A case report details a 68-year-old Black man with chronic obstructive pulmonary disease presenting with acquired ichthyosis.
  • Skin biopsy revealed noncaseating granulomas (sarcoidosis) and ichthyosis vulgaris.

Findings:

  • Ichthyosiform sarcoidosis is uncommon, previously reported in 19 nonwhite patients, primarily with leg lesions.
  • In 76% of cases, skin lesions preceded or coincided with systemic sarcoidosis diagnosis.
  • 95% of patients eventually developed systemic sarcoidosis.

Implications:

Related Experiment Videos

  • Acquired ichthyosis onset warrants investigation for associated conditions including malignancy, autoimmune diseases, and sarcoidosis.
  • A skin biopsy showing acquired ichthyosis may indicate underlying cutaneous sarcoidosis.