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T cell receptor specificity and mimotopes

K Sparbier1, P Walden

  • 1Department of Dermatology, Medical Faculty Charité, Humboldt University, D-10089, Berlin, Germany.

Degeneracy rather than unique ligand specificity seems to guide T cell functions. This view has evolved from analyses of T cell development and responses in vivo, as well as studies with synthetic molecular libraries in vitro, and has opened new prospects both for understanding T cell biology and for applied immunology.

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