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Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
Published on: March 23, 2013
[Determination of food oral-colon transit time with breath hydrogen test]
1Department of Nutrition and Food Hygiene, West China University of Medical Sciences, Chengdu.
Objective:
To establish a method to determine food oral-colon transit time (OCTT).
Methods:
OCTT was determined for five groups of food rich in carbohydrate in 13 healthy adults with breath hydrogen test (BHT) using lactulose as control.
Results:
OCTT was 90.0 +/- 50.6 min, 237 +/- 64.9 min, 341.3 +/- 77.9 min and 352.5 +/- 59.5 min, respectively for lactulose syrup, sweet potato, steamed bun and corn flour, and OCTT could not identified for rice and rice with ground meat due to hydrogen production only in few study subjects or no rising in hydrogen value. OCTT inversely correlated with peak hydrogen value (r = -0.6625) and correlated with the time of peak hydrogen value and food absorption rate (r = 0.7668 and 0.8790).
Conclusion:
BHT is a simple, reliable, non-invasive and feasible method to determine food OCTT.
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