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[Effect of tongxinluo capsule on experimental myocardial ischemia, arrhythmia and hyperlipidemia]
1Department of Basic Medicine, Xiyuan Hospital, China Academy of Traditional Chinese Medicine, Beijing.
Objective:
To study the effects of Tongxinluo capsule (TXLC) on experimental myocardial ischemia and infarction, arrhythmia and hyperlipidemia.
Methods:
Using the methods of epicardial mapping and NBT-ink double staining and the ratio of tissue in myocardial infarction in which the anterior coronary artery was ligated in anesthetized dogs, acute myocardial ischemia was induced with pituitrin and hyperlipidemia was induced with feeding high lipid diet in rats, arrhythmia was induced with chloroform in mice.
Results:
The TXLC reduced significantly the myocardial ischemic limits, degree and the myocardial infarction area, inhibited obviously the ocurrence of arrhythmia and reduced the level of hyperlipidemia.
Conclusion:
The TXLC could improve significantly the myocardial ischemia mycardial infarction and prevent obviously the ocurrence of arrhythmia and hyperlipidemia.