Quality of life in patients receiving home parenteral nutrition
Summary
This summary is machine-generated.Home parenteral nutrition (HPN) significantly reduces quality of life for patients with short bowel syndrome. Assessments using the Sickness Impact Profile and Inflammatory Bowel Disease Questionnaire reveal worse outcomes compared to non-HPN patients.
Area Of Science
- Gastroenterology
- Clinical Nutrition
- Health Outcomes Research
Background
- Quality of life (QoL) is crucial for health technology effectiveness but rarely studied in home parenteral nutrition (HPN) patients.
- Assessing QoL in HPN recipients is vital for understanding treatment impact.
Purpose Of The Study
- To evaluate and compare the quality of life in patients receiving home parenteral nutrition (HPN) versus those with short bowel not on HPN.
- To identify factors influencing QoL in HPN patients.
Main Methods
- A cohort of 49 HPN patients and 36 non-HPN patients with short bowel were assessed.
- The non-disease specific Sickness Impact Profile (SIP) and disease-specific Inflammatory Bowel Disease Questionnaire (IBDQ) were utilized.
- Patient groups were compared based on anatomical or functional short bowel criteria.
Main Results
- HPN patients reported significantly worse overall SIP scores (physical, psychosocial dimensions) compared to non-HPN patients (p<0.001).
- HPN patients also showed significantly lower IBDQ scores overall, particularly in systemic, emotional, and social functioning (p<0.05).
- Having a stoma negatively impacted QoL in HPN patients, unlike in the non-HPN group. Female and older ( >45 years) HPN patients reported worse QoL.
Conclusions
- Quality of life is demonstrably reduced in patients undergoing home parenteral nutrition compared to those with short bowel not requiring HPN.
- The QoL reduction in HPN patients is comparable to that observed in patients with chronic renal failure undergoing dialysis.
- Further research and interventions are needed to improve QoL for HPN patients.
View abstract on PubMed