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Related Experiment Videos

Gender difference in cord serum ferritin concentrations.

T Tamura1, J Hou, R L Goldenberg

  • 1Department of Nutrition Sciences, University of Alabama at Birmingham, 35294-3360, USA. tamurat@uab.edu

Biology of the Neonate
|May 15, 1999
PubMed
Summary

Neonatal iron status, measured by cord serum ferritin, is higher in females than males. This gender difference in iron levels is significant in specific infant and maternal subgroups, impacting neonatal assessment.

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Area of Science:

  • Neonatalogy
  • Pediatric Nutrition
  • Biochemistry

Background:

  • Iron deficiency is a global health concern, particularly in neonates.
  • Cord serum ferritin is a key indicator of neonatal iron status.
  • Understanding factors influencing neonatal iron levels is crucial for early intervention.

Purpose of the Study:

  • To investigate gender differences in cord serum ferritin concentrations.
  • To explore associations between cord serum ferritin and neonatal/maternal characteristics.
  • To determine the relationship between maternal and neonatal iron status.

Main Methods:

  • Measured cord serum ferritin in 255 infants (116 females, 139 males).
  • Analyzed associations with neonatal factors (e.g., birth weight, fetal growth restriction) and maternal factors (e.g., race, age).

Related Experiment Videos

  • Correlated maternal serum ferritin at 36 weeks gestation with infant cord serum ferritin.

    • Main Results:

    • Mean cord serum ferritin was significantly higher in female infants (166 ± 110 μg/L) than males (123 ± 77 μg/L).
    • Gender differences were significant in infants with fetal growth restriction, low birth weight (<3,000 g), and specific maternal demographics.
    • Maternal ferritin correlated with male infant ferritin (r=0.32, p<0.001) but not female infant ferritin (r=0.09, p>0.41).

    Conclusions:

    • Significant gender disparities exist in neonatal iron status at birth.
    • These differences are influenced by various neonatal and maternal factors.
    • Considering infant sex is important for accurate assessment of neonatal iron nutriture.