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[Study on standard of patch test for cosmetic allergens].
1Institute of Occupational Medicine, Chinese Academy of Preventive Medicine, Beijing, China.
Wei Sheng Yan Jiu = Journal of Hygiene Research
|March 1, 1997
Summary
This study established allergen standards for cosmetic patch testing in China. Safe concentrations were determined through animal and human testing, aiding in diagnosing cosmetic-related skin conditions.
Area of Science:
- Dermatology
- Toxicology
- Cosmetic Science
Context:
- Cosmetic products frequently contain allergens.
- China lacks standardized patch test allergen concentrations.
- Accurate allergen identification is crucial for cosmetic safety.
Purpose:
- To establish reliable allergen concentration standards for cosmetic patch testing in China.
- To determine safe and effective concentrations for identifying cosmetic allergens.
- To develop diagnostic criteria for cosmetic-related skin diseases.
Summary:
- 39 common cosmetic allergens were evaluated.
- Animal studies determined safe concentrations, followed by human patch testing on volunteers.
- Concentrations eliciting no reaction in healthy volunteers were verified in patients with eczema or contact dermatitis.
- Positive reaction rates ranged from 0-12%, averaging 3.4%.
Impact:
- Established a series of allergen standards for cosmetic patch testing in China.
- Provides essential data for diagnostic criteria and management principles of cosmetic diseases.
- Enhances the safety assessment of cosmetic products.