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The effect of anthocyanosides on night vision
1Department of Ophthalmology, Assaf Harofeh Medical Center, Tel Aviv University, Israel.
Eye (London, England)
|May 18, 1999
Summary
Anthocyanosides did not significantly improve night vision in normal individuals. This study found no measurable effect on scotopic retinal threshold, dark adaptation rate, or mesopic contrast sensitivity after a single dose.
Area of Science:
- Ophthalmology
- Nutritional Science
- Human Physiology
Background:
- Previous research suggested anthocyanosides may enhance night vision.
- The efficacy of anthocyanosides for improving night vision requires further investigation.
Purpose of the Study:
- To evaluate the effect of single oral doses of anthocyanosides on night vision.
- To assess the impact on scotopic retinal threshold (SRT), dark adaptation rate (DAR), and mesopic contrast sensitivity (MCS).
Main Methods:
- A double-masked, placebo-controlled, cross-over study involving 16 healthy volunteers.
- Administration of single oral doses of 12, 24, or 36 mg of anthocyanosides or placebo.
- Measurement of SRT, DAR, and MCS at baseline and 4, 8, and 24 hours post-administration.
Main Results:
- No significant improvements were observed in SRT, DAR, or MCS within 24 hours.
- The study was powered to detect specific improvements in SRT and MCS.
Conclusions:
- Single oral doses of 12-36 mg anthocyanosides do not appear to significantly affect key night vision parameters.
- Findings suggest limited utility of anthocyanosides for enhancing night vision in healthy individuals.