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Recurrent failure of pronucleus formation after intracytoplasmic sperm injection
1Department of Gynecology and Obstetrics, University of Ulm.
Archives of Gynecology and Obstetrics
|May 18, 1999
Abstract:
We report on a couple with complete fertilization failure in three consecutive trials of intracytoplasmic sperm injection. Some of the unfertilized oocytes were fixed and decondensed sperm heads were found in all of them. It is not clear whether specific defects of the oocyte, abnormalities of sperm chromatin, or a combination of factors are responsible for the observed failure to develop pronuclei.