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Resistive indices in the evaluation of infants with obstructive and nonobstructive pyelocaliectasis
1Department of Radiology, Loyola University Medical Center, Maywood, IL 60153, USA.
Insights
Renal resistive indices from Doppler sonography are not valuable for diagnosing obstructive uropathy in infants. This study found no significant difference in resistive indices between obstructive and nonobstructive cases in this age group.
Area of Science:
- Pediatric Radiology
- Nephrology
- Medical Imaging
Background:
- Renal resistive indices (RI) from duplex Doppler sonography are used to diagnose obstructive uropathy in adults.
- While higher RIs are normal in children, studies suggest their utility in pediatric obstructive uropathy diagnosis using adult criteria (RI ≥ 0.7).
Purpose of the Study:
- To evaluate the effectiveness of Doppler sonography and renal resistive indices in differentiating obstructive from nonobstructive pyelocaliectasis in infants.
Main Methods:
- The study analyzed 43 infants with significant or bilateral pyelocaliectasis.
- Renal resistive indices were calculated using duplex Doppler sonography.
- Comparison of mean RIs and mean inter-kidney RI differences was performed.
Main Results:
- No significant difference was found in the mean resistive indices between the two kidneys within a single patient.
- The mean resistive indices did not differ significantly between obstructive and nonobstructive uropathy groups.
- The mean difference in resistive indices between the two kidneys also showed no significant variation.
Conclusions:
- Doppler sonography, using renal resistive indices, has no diagnostic value in differentiating obstructive from nonobstructive pyelocaliectasis in infants.
- Current adult criteria for RI in diagnosing obstructive uropathy are not applicable to infants.
Abstract:
Diagnosing obstructive uropathy by renal resistive indices calculated from duplex Doppler sonographic waveforms has been supported as well as challenged in the radiology literature relating to adults. Despite reports of normally higher resistive indices in children as compared to adults, two studies have documented high sensitivity and specificity of renal Doppler sonography in the diagnosis of obstructive uropathy in children, using the same discriminatory criterion of a resistive index of 0.7 or greater as used in adults. We evaluated 43 infants with significant or bilateral pyelocaliectasis secondary to both obstructive and unobstructive uropathy and found no significant difference in the mean resistive indices or the mean difference in resistive indices of two kidneys in one patient. We conclude that Doppler sonography in infants has no value in differentiating obstructive from nonobstructive pyelocaliectasis.
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