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Phenelzine-induced sexual dysfunction treated with sildenafil.
S Gupta1, P Masand, A K Ashton
1State University of New York Health Science Center, Syracuse, New York, USA.
Journal of Sex & Marital Therapy
|May 18, 1999
Summary
Phenelzine (Nardil) can cause sexual dysfunction in men, but sildenafil (Viagra) effectively treats this side effect. This case study highlights a successful treatment for antidepressant-induced sexual issues.
Area of Science:
- Pharmacology
- Psychiatry
- Sexual Medicine
Background:
- Phenelzine (Nardil) is a monoamine oxidase inhibitor (MAOI) used to treat depression.
- Sexual dysfunction is a known potential side effect of antidepressant medications, including MAOIs.
- The Arizona Sexual Experiences Scale for males (ASEX-Male) is a validated tool for assessing male sexual dysfunction.
Observation:
- A 56-year-old male patient experienced sexual dysfunction.
- The sexual dysfunction was temporally associated with the initiation of phenelzine treatment.
- The patient's sexual function was evaluated using the ASEX-Male scale.
Findings:
- Sildenafil (Viagra) was administered to address the sexual dysfunction.
- The patient showed a successful resolution of sexual dysfunction following sildenafil treatment.
- The ASEX-Male scale scores indicated significant improvement in sexual function.
Implications:
- Sildenafil is a viable treatment option for phenelzine-induced sexual dysfunction.
- Clinicians should be aware of and screen for sexual side effects associated with phenelzine.
- Further research may explore the efficacy of phosphodiesterase type 5 inhibitors for other antidepressant-induced sexual dysfunctions.