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[Recurrent osteitis and Coxiella burnetii: the relation to chronic recurrent multifocal osteomyelitis]
A Poujol1, S Toesca, J N Di Marco
1Service de pédiatrie, centre hospitalier, Aix-en-Provence, France.
Unlabelled:
Chronic recurrent multifocal osteomyelitis (CRMO) is a disorder of suspected--but unproved-infectious etiology.
Observation:
A girl presented with a typical CRMO involving successively the left fibula, radius, humerus and the right carpus. A Coxiella burnetii infection was indicated during the first attack. Two recurrences occurred in spite of suitable antibiotic treatment and with negative infectious investigation. Two months after stopping antibiotic treatment, a new recurrence associated with antibodies increase and positive bone culture occurred.
Conclusion:
Coxiella burnetii can initiate a CRMO. The mechanism involved is probably a delayed hypersensitivity. CRMO would therefore be the first type of reactive osteitis.