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Updated: Aug 9, 2026

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation
10:52

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation

Published on: January 6, 2016

Synthesis of a new fluorogenic substrate for the continuous assay of mammalian phosphoinositide-specific

A V Rukavishnikov1, T O Zaikova, G B Birrell

  • 1Department of Chemistry, University of Oregon, Eugene 97403, USA.

Bioorganic & Medicinal Chemistry Letters
|May 18, 1999
PubMed

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Phosphoinositides and PIPs01:42

Phosphoinositides and PIPs

Phosphoinositides are a group of phospholipids containing a glycerol backbone with two fatty acid chains and a phosphate attached to a myoinositol sugar ring. The inositol head group extends into the cytoplasm, where it is modified by adding phosphate groups to form phosphatidylinositol phosphates or PIPs.
Different phosphoinositides are synthesized and recruited on the cytosolic face of the plasma membrane. The localization of specific phosphoinositides concentrated in separate membrane...