Long-term effects of balloon angioplasty on systemic hypertension in adolescent and adult patients with coarctation of the aorta
Summary
This summary is machine-generated.Balloon angioplasty effectively treats aortic coarctation hypertension in adolescents and adults, normalizing blood pressure in 74% of patients. This procedure leads to long-term regression of left ventricular hypertrophy.
Area Of Science
- Cardiology
- Interventional Cardiology
- Pediatric Cardiology
Background
- Aortic coarctation is a congenital heart defect requiring intervention.
- Hypertension is a common long-term complication of aortic coarctation.
- Adolescent and adult patients with aortic coarctation often require treatment for associated hypertension.
Purpose Of The Study
- To evaluate the long-term efficacy of balloon angioplasty in managing hypertension in adolescent and adult patients with aortic coarctation.
- To assess the impact of balloon angioplasty on blood pressure control and left ventricular mass in this patient population.
Main Methods
- Balloon angioplasty was performed on 50 patients with discrete, native aortic coarctation.
- Cardiac catheterization and angiography were repeated after 1 year in 42 patients.
- Patients were categorized into two groups based on blood pressure normalization (Group A) or continued need for medication (Group B) and followed annually.
Main Results
- Balloon angioplasty significantly reduced the coarctation gradient and systolic blood pressure immediately after and 1 year post-procedure.
- Group A (normalized blood pressure) showed a significant decrease in systolic blood pressure and left ventricular mass index.
- Group B (persistent hypertension) also experienced a reduction in blood pressure and left ventricular mass, though less pronounced than Group A.
Conclusions
- Balloon angioplasty normalized blood pressure in 74% of patients with aortic coarctation, without the need for medication.
- The procedure resulted in long-term regression of left ventricular hypertrophy.
- Balloon angioplasty is a recommended first-line treatment for native, discrete aortic coarctation in adolescent and adult patients.
View abstract on PubMed