Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Statistical methods of radiation hybrid mapping: selective models].

G R Svishcheva1

  • 1Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russia.

Genetika
|May 20, 1999
PubMed
Summary

New selective models enhance radiation hybrid mapping for combined gene groups, accommodating both strict and non-strict gene retention in hybrid clones. These models are pseudo-Markovian, additive, and suitable for mapping numerous genes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Breeding of the Russian sable: Stages of industrial domestication and genetic variability].

Genetika·2018
Same author

[Functional linear models for region-based association analysis].

Genetika·2018
Same author

[Comparative Estimate of the Sheep Breed Gene Pools using ISSR Analysis].

Genetika·2016
Same author

Some pitfalls in application of functional data analysis approach to association studies.

Scientific reports·2016
Same author

[Estimation of Genetic Diversity of Romanov Sheep by the Coefficient of Genetic Originality Based on ISSR-Fingerprinting Data].

Genetika·2015
Same author

[Influence of anthropogenous factors on the genetic variety of the sable (Martes zibellina L.)].

Molekuliarnaia biologiia·2015

Area of Science:

  • Genetics and genomics
  • Bioinformatics and computational biology

Context:

  • Radiation hybrid mapping is a crucial technique for gene localization.
  • Existing methods have limitations in mapping complex gene groups.

Purpose:

  • To develop novel selective models for radiation hybrid mapping.
  • To extend the capabilities of current gene mapping methodologies.

Summary:

  • Introduced new selective models for radiation hybrid mapping, applicable to combined gene groups detected via molecular or isozyme analysis.
  • These models support both strict and non-strict gene retention, exhibiting pseudo-Markovian and additive properties.
  • The models are validated for mapping an unlimited number of genes, with estimations for minimum gene localization requirements.

Related Experiment Videos

Impact:

  • Enhances the precision and scope of gene mapping studies.
  • Provides a more versatile tool for geneticists and bioinformaticians.
  • Facilitates a deeper understanding of genome organization and gene function.