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Related Experiment Videos

Cocaine associated priapism.

A L Altman1, A D Seftel, S L Brown

  • 1Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA.

The Journal of Urology
|May 20, 1999
PubMed
Summary
This summary is machine-generated.

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Cocaine use can cause difficult-to-treat priapism, a prolonged erection. Early urine toxicology screening is crucial for identifying cocaine abuse and preventing recurrence in affected patients.

Area of Science:

  • Urology
  • Toxicology
  • Emergency Medicine

Background:

  • Cocaine abuse is a significant public health issue in the United States.
  • Priapism, a prolonged erection, is a rare but serious complication linked to cocaine use.
  • Previous reports of cocaine-associated priapism are limited, with none specifically detailing its use in the solid form (crack).

Observation:

  • This study retrospectively analyzed three patients presenting with priapism within a year.
  • All patients had recent cocaine use (within 24 hours) confirmed by urine toxicology, with no other predisposing factors.
  • Patients experienced delays in seeking treatment, complicating therapeutic interventions.

Findings:

  • Standard treatments, including intracavernosal aspiration and irrigation, were unsuccessful in all three cases.

Related Experiment Videos

  • Cavernous-arterial shunting failed in the first two patients.
  • Two cases presented with the high-flow variant of priapism, and one required partial penectomy due to infection and tissue necrosis.

    • Implications:

    • Cocaine can induce refractory priapism, presenting significant treatment challenges.
    • Urine toxicology screening should be considered in patients with unexplained priapism.
    • Identifying and addressing underlying cocaine abuse is essential for preventing recurrent episodes of priapism.