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Antimicrobial activity of diterpene resin acid derivatives
S Savluchinske Feio1, B Gigante, J C Roseiro
1Instituto Nacional de Engenharia e Tecnologia Industrial, IBQTA, Laboratório de Microbiologia Industrial, Azinhaga dos Lameiros, Lisboa, Portugal.
Journal of Microbiological Methods
|May 20, 1999
Abstract:
C-13 deisopropylated and/or C-7 oxidized resin acid derivatives were tested against various microorganisms to determine structural features responsible for biological activity and to determine the influence of the C-13 isopropyl group on antimicrobial activity. Test results show that methyl cis and trans 7-oxo-13-deisopropyldehydroabietate and a mixture of both isomers exhibited activity against fungi and bacteria.