Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postgastrectomy pancreatic malabsorption: is there a case for intervention?

A Griffiths1, R H Taylor

  • 1Department of Gastroenterology, The Royal Hospital, Gosport, Hampshire, UK.

European Journal of Gastroenterology & Hepatology
|May 20, 1999
PubMed
Summary

Patients surviving gastric carcinoma surgery may experience malabsorption. Pancreatic enzyme supplements are not routinely recommended for these patients, as evidence does not support their clinical benefit after gastrectomy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multi-centre real-world evaluation of AI-assisted organ at risk contouring on radiotherapy treatment planning workflows.

The British journal of radiology·2026
Same author

Emotional Eating Interventions for Adults Living With Overweight and Obesity: A Systematic Review and Meta-Analysis of Behaviour Change Techniques.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2025
Same author

Identification of a training shortfall in the operational preparedness of Royal Navy General Duties Medical Officers.

BMJ military health·2024
Same author

A Repurposing Programme Evaluating Transdermal Oestradiol Patches for the Treatment of Prostate Cancer Within the PATCH and STAMPEDE Trials: Current Results and Adapting Trial Design.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023
Same author

Strengthening the equity focus of applied public health research: introducing the FOR EQUITY platform.

Public health·2023
Same author

Report on Surgery for the Fifth Congressional District.

Atlanta medical and surgical journal (1884)·2022

Area of Science:

  • Gastroenterology
  • Surgical Oncology

Background:

  • Increasing survival rates after gastric carcinoma surgery necessitate understanding post-gastrectomy complications.
  • Malabsorption is a significant concern following total gastrectomy, with multifactorial causes.
  • Pancreatic exocrine insufficiency is a proposed contributor to post-gastrectomy malabsorption.

Discussion:

  • While pancreatic insufficiency is documented after gastrectomy, its clinical impact requires evaluation.
  • Factors like loss of gastric reservoir, altered transit, and bacterial overgrowth also contribute to malabsorption.
  • The efficacy of pancreatic enzyme supplementation in improving patient outcomes post-gastrectomy is under scrutiny.

Key Insights:

  • Pancreatic exocrine insufficiency is a recognized issue post-gastrectomy.

Related Experiment Videos

  • Current evidence does not substantiate the routine use of pancreatic enzyme supplements for malabsorption after this surgery.
  • The benefits of enzyme supplementation must be weighed against other contributing factors to malabsorption.

    • Outlook:

    • Further research may clarify the specific patient subgroups who could benefit from pancreatic enzyme therapy.
    • Investigating alternative or adjunctive therapies for post-gastrectomy malabsorption is warranted.
    • Optimizing nutritional support remains crucial for patients undergoing total gastrectomy.