Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Boron is required for zebrafish embryogenesis

Rowe1, Eckhert

  • 1Department of Environmental Health Sciences, University of California, Los Angeles, CA 90095-1772, USA. ceckhert@ucla.edu.

The Journal of Experimental Biology
|May 20, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomechanical correlates for recovering walking speed following a stroke. The potential of tibia to vertical angle as a therapy target.

Gait & posture·2019
Same author

A retrospective analysis of palliative colonic stent placement in an elderly population.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2013
Same author

Poetry and verse: an ideal medium for scientific communication?

Drug discovery today·2000
Same author

DeForMing the AToM. 'Design For Manufacture and Ability To Make should be the modus operandi of all product development departments.'

Pharmaceutical science & technology today·2000
Same author

Measurement of excitation functions in the reactions 197Au(11C, xn)208-xAt using a radioactive 11C beam

Physical review letters·2000
Same author

Reply

The Journal of infectious diseases·2000

Boron is essential for zebrafish embryonic development. Low boron levels caused significant embryo death, particularly during early development, demonstrating its critical role.

Area of Science:

  • Biochemistry
  • Developmental Biology
  • Animal Nutrition

Background:

  • Boron is an essential micronutrient for plants, but its essentiality in animals is not well-established.
  • Previous evidence for boron's essentiality in animals has been largely circumstantial.
  • Understanding boron's role in animal development is crucial for nutritional science.

Purpose of the Study:

  • To investigate the essentiality of boron for embryonic development in zebrafish (Danio rerio).
  • To determine the impact of boron deficiency on zebrafish early development stages.
  • To provide direct evidence for boron's role in vertebrate development.

Main Methods:

  • Zebrafish were raised in low-boron (0.1 µmol L⁻¹) and boron-supplemented (45 µmol L⁻¹) water.

Related Experiment Videos

  • Boron-depleted brine shrimp were used as feed for all zebrafish.
  • Embryo development and survival rates were monitored, and boron content was analyzed.

    • Main Results:

    • Embryos from boron-deficient zebrafish showed a 92% mortality rate within 10 days.
    • The early cleavage stage was most sensitive, with 46% of embryos failing to reach the blastula stage.
    • Repleting boron within the first hour after fertilization rescued embryos from developmental failure.

    Conclusions:

    • Boron is essential for the embryonic development of zebrafish.
    • Boron deficiency severely impacts early zebrafish development, leading to high mortality.
    • This study provides strong evidence for boron's essentiality in vertebrate development.