[The assessment of thyroid gland function in patients with non-insulin dependent diabetes mellitus (type II)]

The aim of the study was to assess thyroid gland function in non-insulin dependent diabetes mellitus patients under different therapeutic regimens. There were examined 75 patients with type II diabetes mellitus, age range 33-80 years (average 65.24 +/- 14.32 years) including 46 women and 29 men. Group I was treated with insulin, group II--with diet, and group III--with sulfonylurea derivatives oral antidiabetic agents. Control group consisted of 91 healthy persons in appropriate age. The highest glucose levels were in insulin treated group--174.17 +/- 40.31 mg%, and were significantly higher from the values observed in oral antidiabetic agents treated group (169.89 +/- 41.34 mg%), and in diet treated group, where glucose levels were the lowest--134.57 +/- 25.06 mg%. In both groups--patients treated with insulin and with oral antidiabetic agents a positive correlation between fT4 and glycated hemoglobin levels were observed. Performed experiments and investigations suggest: 1. There are no differences in thyroid gland function in patients with non-insulin dependent diabetes mellitus. 2. Different therapies (diet, insulin therapy, oral antidiabetic agents) have no influence on thyroid gland function.