Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A solution to diffraction biases in sonoelasticity: the acoustic impulse technique.

S Catheline1, F Wu, M Fink

  • 1Laboratoire Ondes et Acoustique, E.S.P.C.I., Université Paris VII, U.M.R. 7587 C.N.R.S. 1503, Paris, France.

The Journal of the Acoustical Society of America
|May 21, 1999
PubMed
Summary

Estimating viscoelastic properties of soft tissues using shear waves can be biased by reflections and diffraction. Using low-frequency transient excitation accurately measures tissue elasticity and viscosity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A model for decoding resistance in precision oncology: acquired resistance to FGFR inhibitors in cholangiocarcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Staging Chronic Hepatitis B Related Liver Fibrosis with Diffusion-weighted MRI-based Virtual Elastography: Comparisons with Serum Fibrosis Indexes.

Clinical radiology·2024
Same author

Terahertz Imaging Detects Oral Cariogenic Microbial Domains Characteristics.

Journal of dental research·2024
Same author

Trimethylamine Induced Chronic Kidney Injury by Activating the ZBP1-NLRP3 Inflammasome Pathway.

Physiological research·2024
Same author

[LncRNA MAGI2-AS3 enhances cisplatin sensitivity of non-small cell lung cancer cells by regulating the miR-1269a/PTEN/AKT pathway].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2024
Same author

[Research prospect of cyclic nucleotide phosphodiesterase 3/4 inhibitors in chronic obstructive pulmonary disease].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2024

Area of Science:

  • Biophysics
  • Biomaterials Science
  • Medical Imaging

Background:

  • Estimating viscoelastic properties of soft biological tissues is crucial for diagnostics.
  • Current methods utilize low-frequency vibrations (10-500 Hz) and shear wave velocity measurements (approx. 5 m/s).

Purpose of the Study:

  • To identify and address biases in current methods for measuring viscoelastic properties of soft tissues.
  • To propose an improved method for accurate elasticity and viscosity determination.

Main Methods:

  • Theoretical analysis of wave propagation from a piston source, identifying sources of bias (reflections, diffraction, compressional waves).
  • Implementation of low-frequency transient excitation to mitigate identified biases.
  • Experimental validation using phantoms and beef muscle tissue.

Related Experiment Videos

Main Results:

  • Measurement biases in shear wave velocity and attenuation were identified, stemming from boundary reflections, source size, and compressional wave interference.
  • Low-frequency transient excitation effectively avoids these biases.
  • Accurate determination of elasticity and viscosity is achievable with the proposed method.
  • Relative hardness imaging demonstrated successful differentiation of media with varying elasticities in phantoms.

Conclusions:

  • Standard methods for estimating soft tissue viscoelasticity are prone to significant measurement biases.
  • Low-frequency transient excitation offers a robust approach to accurately quantify tissue elasticity and viscosity.
  • This technique holds promise for improved diagnostic imaging and material characterization.