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Antibiotics in chronic suppurative otitis media: a bacteriologic study.
R Indudharan1, J A Haq, S Aiyar
1Department of Otorhinolaryngology, School of Medical Sciences, University Sains Malaysia, Kota Bharu.
The Annals of Otology, Rhinology, and Laryngology
|May 21, 1999
Summary
This study identified Pseudomonas aeruginosa and Staphylococcus aureus as common causes of chronic suppurative otitis media (CSOM). Ciprofloxacin and gentamicin ear drops are recommended as effective topical antibiotics for treating CSOM.
Area of Science:
- Otolaryngology
- Microbiology
- Infectious Diseases
Background:
- Chronic suppurative otitis media (CSOM) requires effective medical management to achieve a dry ear.
- Topical antibiotic ear drops and aural toilet are the primary treatments for non-cholesteatomatous CSOM.
Purpose of the Study:
- To analyze the prevalent microorganisms causing CSOM.
- To determine the antibiotic sensitivity patterns of these isolated organisms.
Main Methods:
- Cultured and identified bacteria from 382 CSOM patient ear swabs.
- Performed antibiotic susceptibility testing on isolated bacterial strains.
Main Results:
- Pseudomonas aeruginosa (27.2%) and Staphylococcus aureus (23.6%) were the most frequently isolated bacteria.
- P. aeruginosa showed high sensitivity to ceftazidime, ciprofloxacin, gentamicin, and polymyxin B.
- S. aureus demonstrated high sensitivity to ciprofloxacin, cloxacillin sodium, cotrimoxazole, and gentamicin.
- Both pathogens exhibited significant resistance to ampicillin, with S. aureus also resistant to polymyxin B.
Conclusions:
- Ciprofloxacin and gentamicin are identified as the most effective topical antibiotic choices for CSOM treatment based on sensitivity profiles.
- Understanding local microbial resistance patterns is crucial for guiding effective CSOM therapy.