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Left atrioventricular plane displacement is related to both systolic and diastolic left ventricular performance in

R Willenheimer1, B Israelsson, C Cline

  • 1Department of Cardiology, Malmö University Hospital, Lund University, Sweden.

European Heart Journal
|May 25, 1999
PubMed

Insights

Left atrioventricular plane displacement reflects both systolic and diastolic function in heart failure patients. This measure is linked to left ventricular filling and fractional shortening, offering insights beyond ejection fraction.

Area of Science:

  • Cardiology
  • Echocardiography
  • Heart Failure Research

Background:

  • Left atrioventricular plane displacement (LAP) is a proposed marker for left ventricular systolic function and prognosis in heart failure.
  • Factors influencing LAP are not fully understood, necessitating further characterization.
  • LAP differs from ejection fraction, requiring investigation into its determinants.

Purpose of the Study:

  • To assess the relationship between left atrioventricular plane displacement and left ventricular diastolic performance.
  • To explore how diastolic function influences this measure of systolic function.

Main Methods:

  • Echocardiography/Doppler assessment in 54 chronic heart failure patients.
  • Measurement of left ventricular diastolic filling parameters, including early transmitral flow deceleration time (Edt).
  • Correlation and multiple regression analyses to identify independent predictors of LAP.

Main Results:

  • LAP significantly correlated with Doppler variables of left ventricular filling, notably log-1 Edt (r = -0.61, P < 0.0001).
  • LAP also correlated with fractional shortening (r = 0.49, P < 0.001).
  • Independent predictors of LAP were log-1 Edt (P = 0.001) and fractional shortening (P = 0.03), with lower LAP in patients with more compromised diastolic function.

Conclusions:

  • Left atrioventricular plane displacement is associated with both systolic and diastolic left ventricular performance.
  • These findings may help explain discrepancies observed between LAP and ejection fraction.
  • LAP provides a comprehensive view of left ventricular function, integrating systolic and diastolic aspects.
Abstract

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