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Psoriasis associated with human immunodeficiency virus in an infant
1Department of Dermatology, New York Medical College-Metropolitan Hospital Center, New York 10029, USA.
Insights
Psoriasis is rarely seen in infants, but this case highlights a 3-month-old with Human Immunodeficiency Virus (HIV) who developed psoriasis. This is the first reported infant case, suggesting a potential link between HIV and psoriasis in early childhood.
Area of Science:
- Dermatology
- Pediatrics
- Infectious Diseases
Background:
- Psoriasis is a chronic inflammatory skin condition often associated with Human Immunodeficiency Virus (HIV) in adults.
- The co-occurrence of psoriasis and HIV in pediatric populations, particularly infants, is not well-documented.
Observation:
- A 3-month-old infant with a diagnosed Human Immunodeficiency Virus (HIV) infection presented with a widespread skin eruption.
- The clinical presentation was consistent with psoriasis, despite the patient's young age.
Findings:
- This case represents the first documented instance of psoriasis in an infant with HIV infection.
- The findings suggest a possible association between HIV and the development of psoriasis in very young children.
Implications:
- This case underscores the importance of considering psoriasis in infants presenting with unusual skin conditions, especially if they have HIV.
- Further research is warranted to explore the immunological mechanisms underlying psoriasis in HIV-infected infants and the potential role of antiretroviral therapy, such as zidovudine.
Abstract:
Psoriasis is commonly reported in association with HIV in adults. A 3-month-old girl with HIV presented with a widespread eruption and was diagnosed with psoriasis. This is the first infant reported with psoriasis in association with HIV infection. The relationship between the two entities is discussed, as is the role of treatment with zidovudine.