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Alzheimer's disease.

E M Reiman1, R J Caselli

  • 1Department of Psychiatry, University of Arizona, Tucson, USA. reiman@samaritan.edu

Maturitas
|May 26, 1999
PubMed
Summary
This summary is machine-generated.

This review covers Alzheimer's disease (AD) clinical and neuropathological aspects, risk factors, diagnostic procedures, and management strategies. It also explores neuroimaging's potential in early detection and prevention of cognitive decline in AD.

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Area of Science:

  • Neurology
  • Neuroscience
  • Geriatrics

Background:

  • Alzheimer's disease (AD) is a progressive neurodegenerative disorder.
  • Understanding its multifaceted nature is crucial for effective management.

Purpose of the Study:

  • To provide a comprehensive review of Alzheimer's disease.
  • To discuss diagnostic procedures, risk factors, and treatment options.
  • To highlight the role of neuroimaging in early detection and prevention.

Main Methods:

  • Literature review of clinical and neuropathological features.
  • Analysis of genetic and non-genetic risk factors.
  • Examination of diagnostic and treatment strategies.
  • Exploration of neuroimaging advancements.

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Main Results:

  • Detailed overview of Alzheimer's disease (AD) clinical and neuropathological characteristics.
  • Identification of key genetic and non-genetic risk factors.
  • Discussion of current diagnostic protocols and therapeutic interventions.
  • Emphasis on neuroimaging's role in identifying pre-symptomatic brain changes.

Conclusions:

  • Comprehensive understanding of AD aids in diagnosis and management.
  • Neuroimaging offers promising avenues for early detection and prevention of cognitive impairment.
  • Integrated approaches are vital for addressing the challenges of Alzheimer's disease.