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Updated: Aug 15, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
11:37

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

A new solid-phase support for oligonucleotide synthesis

R V Devivar1, S L Koontz, W J Peltier

  • 1FlowGenix Corporation, Webster, TX 77598, USA.

Bioorganic & Medicinal Chemistry Letters
|May 26, 1999
PubMed
Summary

A novel polymer colloid solid support was developed for oligonucleotide synthesis, offering a promising alternative to traditional resins. This new system demonstrates comparable performance, enhancing DNA synthesis capabilities.

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