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New growth hormone secretagogues: C-terminal modified sulfonamide-analogues of NN703
1Health Care Chemistry, Novo Nordisk A/S, Novo Nordisk Park, Måløv, Denmark. bpes@novo.dk
Bioorganic & Medicinal Chemistry Letters
|May 26, 1999
Abstract:
The C-terminal the orally active growth hormone secretagogue NN703 was changed to prepare analogues with inverse sulfonamides and inverse amides. The compounds showed high activity in a in vitro rat pituitary model.