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Related Experiment Videos

Measles immunization: early two-doses policy experience.

Y Y al-Mazrou1, M al-Jeffri, O M Ahmed

  • 1Department of Preventive Medicine, Ministry of Health, Riyadh, Saudi Arabia.

Journal of Tropical Pediatrics
|May 26, 1999
PubMed
Summary
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Saudi Arabia

Area of Science:

  • Pediatrics
  • Immunology
  • Public Health

Background:

  • Measles posed a significant threat to infants under one year old in Saudi Arabia, with 50% of cases occurring in 6-8 month olds before 1991.
  • The Expanded Programme on Immunization (EPI) in Saudi Arabia historically faced challenges in measles control among young children.

Purpose of the Study:

  • To evaluate the impact of a two-dose measles vaccination policy on measles incidence across different age groups in Saudi Arabia.
  • To assess the effectiveness of the integrated measles-mumps-rubella (MMR) vaccine as part of the national immunization program.

Main Methods:

  • Implementation of a two-dose measles vaccination schedule (6 and 12 months) in 1991, with the second dose combined with MMR.
  • Monitoring vaccination coverage, which exceeded 90% for the second dose since 1993.

Related Experiment Videos

  • Utilizing routine monthly reports validated by WHO 30-cluster surveys to track measles incidence.

    • Main Results:

    • Significant reduction in measles incidence observed in infants: a 50% drop in 9-11 month olds and over 75% in 6-8 month olds.
    • Measles incidence remained stable in infants under 6 months.
    • Post-policy, 80% of measles cases occurred in children over 5 years, primarily unvaccinated individuals lacking two doses.

    Conclusions:

    • The two-dose measles vaccination strategy has dramatically reduced measles incidence in young children in Saudi Arabia.
    • Achieving measles elimination necessitates continued adherence to the two-dose policy and consideration of broader vaccination measures, such as targeting school-aged children.
    • The policy's success highlights the importance of robust immunization programs in controlling vaccine-preventable diseases.