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Topical aminoglycosides in the management of active mucosal chronic suppurative otitis media
J L Lancaster1, Z G Makura, G Porter
1Department of Otolaryngology, Royal Liverpool University Hospital, UK.
The Journal of Laryngology and Otology
|May 26, 1999
Abstract:
Debate has currently re-emerged following a renewed warning issued from the Committee on the Safety of Medicines (CSM) regarding the relative risk of ototoxicity from the use of aminoglycoside-containing drops in patients with tympanic membrane perforations. We present the findings of a survey of ENT consultants, questioning their views and current practice, and we add to the debate by means of a review and discussion of the literature.